Episode 168: DRCR.net Protocol V Study Results and Real-World Implications


This special edition episode recorded from Vancouver Canada at the 2019 ARVO meeting highlights the DRCR.net Protocol V clinical trial that examined anti-VEGF versus laser versus observation for patients with diabetic macular edema and very good vision. This two part episode starts with two of the senior investigators on the study, Dr. Jennifer Sun and Dr. Carl Baker, discussing the study design and results. For the second half Drs. Emily Chew and George Williams will join the program to discuss real-world implications for practice. The full published manuscript was published in JAMA and is available online at https://jamanetwork.com/journals/jama/fullarticle/2732608

Dr Baker reports receipt of grants for clinical research from Regeneron, Genentech, Allergan, and Novartis. Dr Sun reports receipt of grants from Roche Genentech, Juvenile Diabetes Research Foundation, and Kalvista; personal fees from Current Diabetes ReportsJAMA Ophthalmology, and Merck; and nonfinancial support from Optovue (equipment loaned for research), Roche Genentech (food/beverage), and KalVista (travel support). Drs. Sridhar, Williams, and Chew have no relevant financial disclosures. To claim CME credits for this episode please visit https://www.aao.org/browse-multimedia?filter=Audio&sub=ONE.ContentTypes.Audio.